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Desiccated Thyroid Over The Counter
Your complete guide to over-the-counter natural desiccated thyroid (NDT) supplements

What is natural desiccated thyroid?
Natural desiccated thyroid (NDT), also called thyroid extract, is a dried powdered thyroid gland from an animal — usually from a pig (porcine thyroid), but it can also come from a cow (bovine thyroid). NDT contains all the thyroid hormones naturally produced by the thyroid gland: T4, T3, T2, T1, and calcitonin.
This guide is for people who want to try an over-the-counter thyroid supplement without needing a prescription. It covers everything you need to know to purchase the right product and use it safely and effectively.
This guide includes
- ✓What natural desiccated thyroid (NDT) is and how it differs from synthetic thyroid hormone.
- ✓Why NDT contains both T4 and T3, simulating the natural hormone production of the thyroid gland.
- ✓The best over-the-counter NDT supplement brands available without a prescription.
- ✓How to use NDT safely and how to evaluate its effects using pulse, temperature, and symptoms.
- ✓How to start slowly and adjust your dose to avoid side effects.
- ✓The difference between porcine (pig) and bovine (cow) thyroid extract.
- ✓How NDT compares to prescription thyroid medication.
- ✓How to combine NDT with progesterone and pregnenolone for optimal results.
- ✓When to consider upgrading to prescription thyroid medication.
Important note
If you do not have a prescription for thyroid hormone, this guide can help you find good brands of over-the-counter (OTC) thyroid supplements. For prescription thyroid medication, see our Thyroid Medication Guide.
Hormonal Support Guide
Combining NDT with progesterone and pregnenolone for best results.
Read more →Thyroid Medication Guide
Prescription T3, T4 and natural desiccated thyroid medication explained.
Read more →Need help fine-tuning your thyroid support?
Book a private consultation with Dr. Benedicte Lerche for personalised guidance on NDT dosing and thyroid therapy.
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