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Thyroid Health22 January 2021

What Every Hypothyroidism Patient Should Know

Dr. Benedicte Lerche — About
Dr. Benedicte Lerche

MSc PhD · Biochemist & Metabolic Health Expert

Published 22 January 2021

· Updated 22 July 2026

· 4 min read

Hypothyroidism – How To Find The Right Treatment?

The reason why it is hard to find the right treatment plan for hypothyroidism is that the old ways of treating low thyroid function have been lost, and doctors nowadays are not taught to listen to the patient's symptoms — instead, they go by blood test only.

How To Overcome Hypothyroid Symptoms

My treatment method takes diet, supplements, correct medication, and hormonal support into account. I have developed online programmes and counselling services to help you do this step by step.

Can Changing Your Diet Affect Your Thyroid?

Most people on a normal western diet are eating foods that directly inhibit thyroid function and depriving the body of essential food groups which can promote good hormonal balance. My health method includes a thyroid promoting diet that addresses these issues directly. You can learn more in my book How to Boost Metabolism with Food and my Metabolic Nutrition Mastery course.

What Is The Best Medication For Hypothyroidism?

The best thyroid medication is a mixture of T4 and T3. T3 is the active thyroid hormone that promotes cellular energy production, whereas T4 is a storage hormone which is turned into T3 in the body's tissues.

Most doctors treat hypothyroidism with a T4-only medication (levothyroxine) such as L-Troxin or Synthroid, and that can create serious issues of T4 poisoning, as too much T4 has anti-thyroid effects on its own.

You can learn more about my recommendations for proper thyroid medication in my book How to Use Thyroid Medication and my Thyroid Recovery & Renewal course.

Is There Side Effects Of Thyroid Medication?

Starting up on thyroid medication can be difficult and in the beginning, taking thyroid medication can actually worsen symptoms. Therefore starting up on thyroid medication has to be done very slowly, especially if you are severely hypothyroid.

In addition, using supplementation of the body's natural hormones pregnenolone and/or progesterone can relieve the negative stress symptoms which sometimes occur as a result of pushing the metabolic rate to a higher level. I cover this in detail in my Hormone Rebalance Intensive™.

Frequently Asked Questions

Why is it so hard to find the right treatment for hypothyroidism?

The old ways of treating low thyroid function have been largely lost. Modern medicine is taught to rely on blood tests alone, rather than to listen to the patient's symptoms. This means many people with genuine hypothyroid symptoms are told their levels are "normal" and sent away without treatment. A comprehensive approach needs to take diet, supplements, the right type of medication, and hormonal support all into account.

Why is T4-only medication often not enough?

T4 is a storage hormone — it only becomes active when the body converts it to T3. If your conversion is impaired, T4-only medication leaves you without enough active thyroid hormone and can eventually lead to T4 accumulation, which has anti-thyroid effects on its own. A medication that contains both T4 and T3 more closely mimics what a healthy thyroid gland produces naturally. I cover this in detail in my book How to Use Thyroid Medication.

Why does starting thyroid medication sometimes make symptoms worse?

Increasing thyroid function raises the metabolic rate, which can temporarily amplify stress responses and create symptoms such as palpitations, anxiety, and disturbed sleep — particularly if the adrenal system is already under strain. Starting very slowly, and in some cases supporting the body with natural protective hormones such as progesterone and pregnenolone, can make the transition much smoother. I cover these starting protocols in my Thyroid Recovery & Renewal course.

How do progesterone and pregnenolone help with thyroid treatment?

Progesterone and pregnenolone are the body's natural protective hormones. They counteract the stress hormones that rise when metabolism increases, relieving symptoms like anxiety, palpitations, and sleep disturbance that can occur when starting thyroid medication. They also have direct benefits for hormonal balance and thyroid function in their own right. I explain how to use them in my Hormone Rebalance Intensive™.

Topics

hypothyroidismthyroid healththyroid symptomsthyroid treatmentpro-metabolic
Dr. Benedicte Lerche MSc PhD — Biochemist and metabolic health expert

About the Author

Dr. Benedicte Lerche MSc PhD

Biochemist · Metabolic Health Expert · Author

Dr. Benedicte Lerche holds a Master's degree and PhD in biochemistry. After being diagnosed with hypothyroidism and finding that conventional treatment left her symptoms unresolved, she turned to Dr. Ray Peat's pro-metabolic research — and eventually restored her own thyroid function and health. She now dedicates her work to helping others do the same through evidence-based books, online courses, and one-on-one counseling.

Read Dr. Lerche's full story →
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